Trained immunity: a new avenue for tuberculosis vaccine development
نویسندگان
چکیده
منابع مشابه
Trained immunity: a new avenue for tuberculosis vaccine development.
Adaptive immunity towards tuberculosis (TB) has been extensively studied for many years. In addition, in recent years the profound contribution of innate immunity to host defence against this disease has become evident. The discovery of pattern recognition receptors, which allow innate immunity to tailor its response to different infectious agents, has challenged the view that this arm of immun...
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There is an urgent need for new and better vaccines against tuberculosis (TB). Current vaccine design strategies are generally focused on the enhancement of cell-mediated immunity. Antibody-based approaches are not being considered, mostly due to the paradigm that humoral immunity plays little role in the protection against intracellular pathogens. Here, we reappraise and update the increasing ...
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ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 2015
ISSN: 0954-6820
DOI: 10.1111/joim.12449